DNA Fragmentation Index (DFI): Understanding Sperm DNA Damage in Male Infertility & IVF Failure
For decades, routine semen analysis (evaluating sperm count, motility, and morphology) has served as the baseline diagnostic test for male fertility. However, up to 15% of men experiencing fertility difficulties present with completely normal routine semen parameters. Routine semen analysis evaluates external physical characteristics. It does not reveal the genetic integrity inside the sperm head.
